Sticky situation

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A sticky situation

Candida albicans is a commensal microorganism of the human microbiome; it is also the most prevalent fungal pathogen of humans. Many infections caused by C. albicans are a direct consequence of its proclivity to form biofilms--resilient, surface-associated communities of cells where individual cells acquire specialized properties that are distinct from those observed in suspension cultures. We ...

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A sticky situation

The whirling helical structure obtained when pouring honey onto toast may seem like an easy enough problem to solve at breakfast. Specifically, one would hope that a quick back-of-the-envelope scaling argument would help rationalize the observed behaviour and predict the coiling frequency. Not quite: multiple forces come into play, both in the part of the flow stretched by gravity and in the co...

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Ocular trauma: a sticky situation.

DESCRIPTION A 38-year-old man was struck by a branch in the right eye while riding a quad bike between trees. In the emergency department he was documented to have a seemingly intact globe, but with a linear corneal laceration and a small hyphaemapresumablysecondarytoblunttrauma(figure1). There was no evidence of aqueous leakage after the application of fluorescein and the anterior chamber was ...

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Cell Adhesion: Sizing Up a Sticky Situation

Cadherins, the principal cell adhesion molecules in animal tissues, come in clusters. A combination of super-resolution microscopy and modeling now reveals the sizes of these clusters and gives clues to how they are assembled.

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A sticky situation: the unexpected stability of malaria elimination

Malaria eradication involves eliminating malaria from every country where transmission occurs. Current theory suggests that the post-elimination challenges of remaining malaria-free by stopping transmission from imported malaria will have onerous operational and financial requirements. Although resurgent malaria has occurred in a majority of countries that tried but failed to eliminate malaria,...

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ژورنال

عنوان ژورنال: Nature Reviews Cancer

سال: 2003

ISSN: 1474-175X,1474-1768

DOI: 10.1038/nrc1067